PHARMACEUTICAL TECHNOLOGY complete syllabus

 

	PHARMACEUTICS-VII (PHARMACEUTICAL TECHNOLOGY) (Theory)
Paper 3	Marks 100

 

1.     PRINCIPLES OF PHARMACEUTICAL FORMULATION AND DOSAGE FORM DESIGN:

                        Need for dosage form; Pre-formulation Studies; Product Formulation.

 

2.     ADVANCED GRANULATION TECHNOLOGY (DESIGN & PRACTICE): 

      Spray Drying Granulation Technology; Roller Compaction Technology; Extrusion/Spheronization as a Granulation Technique; Single-Pot Processing Granulation Technology: Rapid Release Granulation Technique; Particle Coating by Centrifugation Granulation Technology.

 

3.     POLYMERS USED IN DRUG DELIVERY SYSTEMS:

 

4.     NOVEL DRUG DELIVERY SYSTEM (DDS):

Sustained/ Controlled Release Drug Delivery System

                                  i.     Microencapsulation technique

•   Coacervation

•   Solvent evaporation

•   Interfacial polymerization

•   Spray drying ii.  Developmental aspects of Matrix and   Reservoir Systems

5.     NOVEL GIT DRUG DELIVERY SYSTEM (DDS):  Oral Osmotic Pumps

•       Ion-Exchange Controlled DDS

•       pH-Controlled DDS

•       Bio/mucoadhesive DDS

•       Floating DDS

 

6.     DRUG CARRIER SYSTEM:  Liposomes

 Niosomes

 

7.     TARGETED DRUG DELIVERY SYSTEM:

•       Active Drug Delivery System

•       Passive Drug Delivery System

 

8.     PHARMACEUTICAL BIOTECHNOLOGY:

a.       Introduction to Biotechnology: Genetics/Genomics, Proteomics, Biomolecular target Identification, Pharmacogenomics, Gene therapy and Nucleic acid therapeutics.

b.       Techniques Used in Pharmaceutical biotechnology: PCR, DNA Sequencing, Affinity Protein Purification.

c.       Fundamentals of Genetic Engineering and its Application in Medicine

d.       Pharmaceutical Recombinant therapeutic Proteins, Growth factors, Therapeutic antibodies, High-throughput screening of putative therapeutic compounds.

e.       Biotechnological aspects in the product development

f.        Principle, Synthesis and Application of Monoclonal Antibodies

Immobilized Enzymes and their application in Medicine