MICROBIOLOGY-PHARMACEUTICS-III complete syllabus

 

 

PHARMACEUTICS-III (PHARM. MICROBIOLOGY & IMMUNOLOGY) (Theory)

Paper 4                                                                                                                                                                                                        Marks 100

 

NOTE: The topics will be taught with special reference to their Pharmaceutical Applications.

 

1.     GENERAL MICROBIOLOGY: Historical introduction, Scope of microbiology with special reference to Pharmaceutical Sciences. Nomenclature and classification of Micro-organisms.

2.     MICRO-ORGANISMS:

a.     The Bacteria: General and cellular Morphology, structure and function. Classification of Bacteria. Growth curve, growth factors and growth characteristics. Nutrition requirements and nutrition factors affecting growth. Culture Media, Bacterial cultures and staining Methods.

b.     The Viruses: Introduction, Classification (and detail of at least one species from every group), cultivation and replication.

c.     The Fungi/Yeast/Molds:

d.     The Protozoa:

3.     THE NORMAL FLORA: Microbiology of air, water and soil (general introduction and normal inhibitants of air, water and soil).

4.     INDUSTRIAL MICROBIOLOGY: Introduction to Sterilization/ Disinfection. Fermentation. Pharmaceutical products Produced by fermentation process (Penicillins, Cepalosporins, Gentamycin, Erythromycin, Tetracyclines, Rifamycin, Griseofulvin).

5.     IMMUNOLOGY: Introduction and types of Immunity: Specific and non-specific (Cellular basis of Immune response. Immunity, autoimmunity, tolerance. Antigen. Antibodies). AntigenAntibody reactions and their clinical and diagnostic applications. Hypersensitivity and allergy. Drug allergy mechanism. Vaccination: Introduction and aims. Types of Vaccines. Current vaccine practices. 

6.     FACTORY AND HOSPITAL HYGIENE       AND       GOOD            MANUFACTURING

PRACTICES: Introduction, Control of microbial contamination during manufacture, Manufacturing of Sterile products, A Guide to Current Good Pharmaceutical Manufacturing Practices.

7.     INTRODUCTION TO DISEASES: Dengue fever, Bird flu, SARS or other prevailing diseases of bacteria and virus.

PHARMACEUTICS-III (PHARM. MICROBIOLOGY & IMMUNOLOGY) (Practical)

Paper 10                                                                                                                                                                                                                                                                                                                      Marks 100

 

NOTE: Practical of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Sterilization of Glassware and pharmaceutical products by various methods. Microbiological assays of Anti-biotics and vitamins. Preparation of general and selective Media and culturing of micro-organisms. Total and viable counts of microorganism. Morphological and selective biochemical characterization of some specimen. Staining of Bacteria: Gram method, Acid fast, Giemasas staining, Capsule staining, Flagella staining and Spore staining. Microbiological analysis of air, water and soil (Note: A minimum of 20 practicals will be conducted).